Nucleic Acids Research Kevin Debatisse, Manon Brunie, Baptiste Darracq, Elia Bandini, Eloi Littner, Eduardo P C Rocha, Didier Mazel, Céline Loot Summary Integrons act as biobanks of gene cassettes conferring functions crucial for bacterial defense, including protection against phages and antibiotics. They enable bacterial on-demand adaptation through capture and shuffling of the cassettes under stress conditions. Our results underscore the significant role of horizontal gene

Communications medicine Bloch, E., Baudemont, G., Donnadieu, F. et al.  Investigation of the sero-epidemiology of vaccine preventable diseases and common viral infections in French populations. Background Vaccine-preventable diseases and common viral infections pose substantial public health challenges worldwide. Applying multiplex serological assays to samples collected from cross-sectional studies allows assessment of population-level immunity to a broad range of pathogens.

Communications Biol ogy Boetto, C., Romero, V.B., Henches, L. et al.  The influence of environment on bacterial co-abundance in the gut microbiomes of healthy human individuals. Summary The gut microbiome is a complex ecosystem characterized not only by its marginal taxonomic composition but also by its emergent properties. Bacteria develop local interactions to form coherent functional communities, whose effects on health and diseases cannot be predicted from the behavior of

Nature Methods Huizing, GJ., Samaran, J., Capocefalo, D. et al. Summary In dynamic biological processes such as development, spatial transcriptomics is revolutionizing the study of the mechanisms underlying spatial organization within tissues. Inferring cell fate trajectories from spatial transcriptomics profiled at several time points has thus emerged as a critical goal, requiring novel computational methods. Wasserstein gradient flow learning is a promising framework for an